| Product Name | Mouse anti-Keratin 18, clone RCK106, Purified (Monoclonal) |
|---|---|
| Description | Mouse anti-Keratin 18, clone RCK106, Purified (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | RCK106 |
| Immunogen | Cytokeratins from the Human bladder carcinoma cell line T24 |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-Fr, FC, ICC, IHC-P, WB |
| Working Dilutions | ,,,, |
| Diluent Buffer | PBS with 0.09% sodium azide |
| Concentration | 1 mg/ml |
| Storage | 2-8°C |
| Notes | Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual Human Cytokeratins are numbered 1 to 20. The various epithelia in the Human body usually express Cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of matuRation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The Cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. |
| References | Ramaekers et al. Exp Cell Res 1987;170:235-249. Raats et al. Cell Biol 1990;111:1971-1985. Smedts et al. Am J Pathol 1990;136:657-668. Schaafsma et al. Am J Pathol 1990;136:329-343. Bonfrer et al. Tumour Biol 1994;15:210-222 |
| Supplier | MONOSAN |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
