| Product Name | Mouse anti-Macrophages, clone LN-5 (Monoclonal) |
|---|---|
| Description | Mouse anti-Macrophages, clone LN-5 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | LN-5 |
| Immunogen | deparaffinized cell extracts of peripheral blood mononuclear cells |
| Isotype | IgM |
| Reactivity | Human |
| Applications | IHC-Fr, FC, IF, IHC-P |
| Working Dilutions | ,,, |
| Diluent Buffer | PBS with 0.02% sodium azide |
| Concentration | 100 ug/ml |
| Storage | 2-8°C |
| Notes | LN-5 reacts with human macrophages and displays lymph node germinal center and mantle zone B cell reactivity. It reacts with interdigitating reticulum cells, with tingible body and sinus histiocytes. It further reacts with certain tumor cells and also with normal nonlymphoid tissue like chief cells of the stomach and spermatogonia. LN-5 is negative on Hodgkin's disease and non-Hodgkin's lymphomas. |
| References | Bhoopat, L. et al. Immunhistochemical characterization of two new monoclonal antibodies (LN-4, LN-5) reactive with human macrophage subsets and derived malignancies in B5-fixed paraffin-embedded tissues. Blood 71: 1079-1085, (1988) |
| Supplier | MONOSAN |
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