| Product Name | Mouse anti-MRP1, clone MRPm5 (Monoclonal) |
|---|---|
| Description | Mouse anti-MRP1, clone MRPm5 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | MRPm5 |
| Immunogen | bacterial fusion protein of MRP1 amino acids 986-1204 |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | IHC-Fr, FC, ICC, IHC-P, WB |
| Working Dilutions | ,IHC-P (1:20),,,WB (1:50) |
| Form | Protein G purified |
| Diluent Buffer | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration | 100 ug/ ml |
| Storage | 2-8°C |
| Notes | The antibody reacts with an internal epitope of MRP1, a 180-195 kD transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPm5 was raised against a bacterial fusion protein of MRP1, containing amino acids 986-1204 of the protein. MRPm5 does not cross-react with the human MDR1 and MDR3 gene products. |
| References | Cole S et al. Science 1992; 258: 1650-1654. Flens M et al. Cancer Res 1994; 54: 4557-4563. Zaman et al. Proc Nat Acad Sci 1994; 91: 8822-8826. Schadendorf et al. Am J Pathol 1995; 147: 1545-52. Nooter et al. Clin Cancer Res 1995; 1: 1301-10 |
| Supplier | MONOSAN |
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