| Product Name | Mouse anti-Myeloid Specific Antigen, clone BM-3 (Monoclonal) |
|---|---|
| Description | Mouse anti-Myeloid Specific Antigen, clone BM-3 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | BM-3 |
| Immunogen | nuclei from Pokeweed mitrogen stimulated human peripheral blood lymphocytes |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-Fr, IF, IP |
| Working Dilutions | ,, |
| Diluent Buffer | PBS with 0.02% sodium azide |
| Concentration | 100 ug/ml |
| Storage | 2-8°C |
| Notes | Induction studies using HL-60 cells showed that BM-3 identifies a nuclear antigen which is expressed during the early phases of myeloid differentiation, making BM-3 an early marker of myeloid differentiation. It is found in 98% of human granulocytes, in 80% of human monocytes and in myeloid precursor cells, residing in lymphoid and non-lymphoid tissues. It also reacts with a subset of myeloid leukemia cells. BM-3 has no reactivity with any other cell type in human tissues. In experiments using S-35 methionine labeled human myeloid leukemia cells BM-3 immunoprecipitated a 13 kDa protein. |
| References | Epstein, AL et al. Blood 70:1124-1130 (1987). Murao et al, Cancer Research 45: 791-795 (1985) |
| Supplier | MONOSAN |
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