| Product Name | Mouse anti-P193/VPARP, clone P193-10 (Monoclonal) |
|---|---|
| Description | Mouse anti-P193/VPARP, clone P193-10 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | P193-10 |
| Immunogen | VPARP aa 408-611 |
| Isotype | IgG2b k |
| Reactivity | Human |
| Applications | IHC-Fr, FC, IHC-P, WB |
| Working Dilutions | IHC-P (1:10-1:20),,, |
| Diluent Buffer | PBS with 1% BSA and 0.1% sodium azide |
| Concentration | 250 ug/ ml |
| Storage | 2-8°C |
| Notes | p193-10 reacts with an internal epitope (amino acids 506-510, VALGK) of the minor vault protein (p193 or VPARP), which is overexpressed in various human non-P-glycoprotein MDR tumor cell lines, accordingly to an increase in the number of vault particles. p193-10 was raised against an E. coli lysate transformed with the pET28a(+) expression vector containing amino acids 408-611 of the p193 cDNA. |
| References | Schroeijers AB et al. Cancer Res 2000; 60: 1104. Kickhoefer VA et al. J Cell Biol 1999; 146: 917. Kickhoefer VA et al. J Bio Chem 1998; 273: 8971. Scheper RJ et al. Cancer Res 1993; 53: 1475. Scheffer GL et al. Nature Med 1995; 1: 578 |
| Supplier | MONOSAN |
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