Mouse anti-SNAP-25 26-27kDa, clone SP12 (Monoclonal)

Category: Antibodies
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MON8063
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Product Name Mouse anti-SNAP-25 26-27kDa, clone SP12 (Monoclonal)
Description Mouse anti-SNAP-25 26-27kDa, clone SP12 (Monoclonal)
Host Mouse
Clonality Monoclonal
Clone SP12
Immunogen Crude human synaptic immunoprecipitate.
Isotype IgG1
Reactivity Rodent, Hamster, Human, Porcine, Rat
Applications ELISA, IHC-P, WB
Working Dilutions ,,
Diluent Buffer PBS with 0.09% sodium azide
Concentration 1.0 mg/ml
Storage 2-8°C
Notes Mouse anti Human SNAP-25 antibody, clone SP12 recognizes the human pre-synaptic protein, SNAP-25, also known as Synaptosomal-associated protein 25, Super protein (SUP) or Synaptosomal-associated 25 kDa protein. SNAP-25 is a 206 amino acid presynaptic protein of ~25 kDa containing two t-SNARE coiled-coil homology domains. Mouse anti human SNAP-25 antibody, clone SP12 will recognize SNAP-25 fusion protein from COS cells, but not the fusion protein from bacterial systems.Mouse anti Human SNAP-25 antibody, clone SP12 has been used to study the distribution of synaptic changes in the hippocampus of patients with medically refractory temporal lobe epilepsy. (Honer et al. 1994).
References Dickson, D.W. et al. (1995) Correlations of synaptic markers with cognitive status in prospectively studied elderly humans. Neurobiol. Aging 16: 285-98
Supplier MONOSAN

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