Mouse anti-TNF-Alpha, clone T1 (Monoclonal)

Category: Antibodies
Catalog
MON9068
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Product Name Mouse anti-TNF-Alpha, clone T1 (Monoclonal)
Description Mouse anti-TNF-Alpha, clone T1 (Monoclonal)
Host Mouse
Clonality Monoclonal
Clone T1
Immunogen Unknown or proprietery to MONOSAN and/or its suppliers
Isotype IgG1
Reactivity Human
Applications ELISA, FA, FC, WB
Working Dilutions ,,,
Diluent Buffer PBS with 0.1% BSA and 0.02% sodium azide
Concentration 100 ug/ ml
Storage 2-8°C
Notes The antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. The antibody inhibits the biological activity of both forms. It does not react with receptor bound TNF-alpha. It can be a useful tool to discriminate between the membrane form of TNF expressed on producer cells and the proteolytically cleaved, soluble TNF-alpha bound to its cognate cell membrane receptors (TNF-RI and TNF-RII). For this purpose we recommend to use this antibody in combination with the anti-TNF-alpha antibody HM2026, which recognizes soluble, membrane and receptor bound TNF-alpha.
References Gerspach; J et al. Microsc Res Tech 2000; 50: 243
Supplier MONOSAN

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