| Product Name | MRGPRX2 Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against MRGPRX2 conjugated to Biotin. |
| Synonyms | G protein coupled receptor MRGX 2 antibody; G protein coupled receptor MRGX2 antibody; Mas related G protein coupled receptor member X2 antibody; Mas related gene MRGX 2 antibody; Mas related gene MRGX2 antibody; MAS related GPR member X2 antibody; Mas-related G-protein coupled receptor member X antibody; Mas-related G-protein coupled receptor member X2 antibody; MRGPRX 2 antibody; MRGPRX2 antibody; MRGX 2 antibody; MRGX2 antibody; MRGX2_HUMAN antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human Mas-related G-protein coupled receptor member X2 protein (286-330AA) |
| Isotype | IgG |
| Target | MRGPRX2 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q96LB1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A. |
| Supplier | Cusabio |
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