| Product Name | MSH4 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to MSH4 |
| Synonyms | hMSH4 antibody; MSH 4 antibody; MSH4 antibody; MSH4_HUMAN antibody; MutS homolog 4 (E. Coli) antibody; MutS homolog 4 antibody; MutS protein homolog 4 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human MSH4 |
| Isotype | IgG |
| Target | MSH4 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | O15457 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. |
| Supplier | Cusabio |
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