| Product Name | Neurotensin |
|---|---|
| Description |
Neurotensin is an endogenous neurotransmitter and hormone, found in both neuronal synaptic vesicles, and in neuroendocrine cells in the periphery. Neurotensin acts through three receptors and is involved in several important biological functions, including analgesia and hypothermia, and also food intake and glucose homeostasis. Neurotensin receptors also have a role in promoting tumour cell proliferation, migration and DNA synthesis. Expression of neurotensin and its receptors has been correlated to cancer prognosis and prediction of treatment. |
| Synonyms | 39379-15-2, Neurotensin, XLYENKPRRPYIL |
| Molecular Weight | 1672.94 Da |
| Target | Neurotensin receptors |
| Amino Acid Sequence | XLYENKPRRPYIL |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 39379-15-2 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: X is Glp |
| References |
Vincent et al (1999) Neurotensin and neurotensin receptors. TiPS 20 302 PMID: 10390649Tyler-McMahon (2000) Neurotensin: peptide for the next millenium. Regul.Pept. 93 125 PMID: 11033059Mazella et al (2012) Neurotensin and its receptors in the control of glucose homeostasis. Front Endocrinol. 3 143 PMID: 23230428 Related areasAll peptides >All neurotensin receptor modulators >All endocrinology research areas >All neuroscience research categories >All appetite regulation research categories >All pain research categories >All cancer research categories > |
| Supplier | Isca Biochemicals Limited |
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