NFIL3 Monoclonal Antibody

Category: Antibodies
Catalog
E-AB-27747
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Product Name NFIL3 Monoclonal Antibody
Description NFIL3,also named as E4BP4 and IL3BP1,belongs to the bZIP family and NFIL3 subfamily. It represses transcription from promoters with activating transcription factor (ATF) sites. NFIL3 activates transcription from the interleukin-3 promoter in T-cells. It competes for the same consensus-binding site with PAR DNA-binding factors (DBP,HLF and TEF). It is a component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. NFIL3 protects pro-B cells from programmed cell death. It is a key regulator of TH2 responses.
Synonyms E4 promoter binding protein 4,E4BP4,IL3BP1,NF IL3A,NFIL3,NFIL3A
Host Mouse
Clone 2F4B4
Immunogen Fusion Protein of NFIL3
Isotype IgG1
Reactivity Human
Applications ELISA, WB
Form PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Uniprot Q16649
Background NFIL3,also named as E4BP4 and IL3BP1,belongs to the bZIP family and NFIL3 subfamily. It represses transcription from promoters with activating transcription factor (ATF) sites. NFIL3 activates transcription from the interleukin-3 promoter in T-cells. It competes for the same consensus-binding site with PAR DNA-binding factors (DBP,HLF and TEF). It is a component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. NFIL3 protects pro-B cells from programmed cell death. It is a key regulator of TH2 responses.
Supplier Elabscience

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