| Product Name | (NLysNspeNspe)4-NH2 |
|---|---|
| Description | Peptoids are peptide-mimicking poly-N-substituted glycines, which exhibit enhanced physiological stability and are known to have antibacterial and antiparasitic qualities. They have recently been shown to have activity against Leishmania mexicana axenic amastigotes. NLys is the N-substituted lysine peptoid monomer and Nspe is the (S)-(N-1-phenylethyl)glycine peptoid monomer |
| Synonyms | NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe-NH2, Peptoids, antibacterial, antiparasitic, poly-N-substituted glycines |
| Molecular Weight | 1819.3 Da |
| Target | Antibacterials |
| Amino Acid Sequence | NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe-NH2 |
| Form | Freeze dried solid |
| Purity | >90% By HPLC |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: NLys is the N-substituted lysine peptoid monomer and Nspe is the (S)-(N-1-phenylethyl)glycine peptoid monomer For more information about peptoids and their nomenclature please refer to the peptide resources page |
| References |
Chongsiriwatana et al (2008) Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc. Natl. Acad. Sci 105(8) 2794 DOI: 10.1073/pnas.0708254105 Zuckermann (2011) Peptoid origins. Biopolymers, 96 545 doi:10.1002/bip.21573 Sun and Zuckermann (2013) Peptoid Polymers: A Highly Designable Bioinspired Material. ACS Nano 7(6) 4715 https://doi.org/10.1021/nn4015714 Huang et al (2014) Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity. PLoS ONE 9(2) e90397. https://doi.org/10.1371/journal.pone.0090397 Eggimann et al (2015) Investigating the Anti€leishmanial Effects of Linear Peptoids. ChemMedChem. 10 233 doi:10.1002/cmdc.201402416 Related areas All peptoids >All antibacterials > |
| Supplier | Isca Biochemicals Limited |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
