NONO Monoclonal Antibody

Category: Antibodies
Catalog
E-AB-27748
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Product Name NONO Monoclonal Antibody
Description Non-pou domain-containing octamer-binding protein(NONO),other named p54nrb,belongs to DBHS family,whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes,such as the regulation of circadian rhythm,carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ,and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components,pre-mRAN 3'-end formation,cAMP cycling and transcriptional activation.
Synonyms 55 kDa nuclear protein,NONO,NonO protein,NRB54,P54,p54(nrb),P54NRB
Host Mouse
Clone 2A2B10
Immunogen Fusion Protein of NONO
Isotype IgG1
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Form PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Uniprot Q15233
Background Non-pou domain-containing octamer-binding protein(NONO),other named p54nrb,belongs to DBHS family,whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes,such as the regulation of circadian rhythm,carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ,and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components,pre-mRAN 3'-end formation,cAMP cycling and transcriptional activation.
Supplier Elabscience

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