| Product Name | NRAS Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to NRAS |
| Synonyms | ALPS4 antibody; AV095280 antibody; GTPase NRas antibody; HRAS1 antibody; N ras antibody; N ras protein part 4 antibody; Neuroblastoma RAS viral (v ras) oncogene homolog antibody; NRAS antibody; NRAS1 antibody; NS6 antibody; OTTHUMP00000013879 antibody; OTTMUSP00000023521 antibody; RASN_HUMAN antibody; Transforming protein N Ras antibody; Transforming protein N-Ras antibody; v ras neuroblastoma RAS viral oncogene homolog antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human NRAS |
| Isotype | IgG |
| Target | NRAS |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | P01111 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
| Supplier | Cusabio |
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