| Product Name | OVA (257-264) |
|---|---|
| Description |
OVA (257-264) is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA(257-264) is an antigenic peptide and has been used to trigger T cell activation in immunology studies. OVA (257-264) has been used to sensitize mice to generate an asthmatic model, in the stimulation of splenocytes and for treating dendritic cells to be used as a positive controls in cross-presentation studies. |
| Synonyms | Ovalbumin (257-264) (chicken) |
| Molecular Weight | 963.13 Da |
| Target | Epitopes |
| Amino Acid Sequence | SIINFEKL |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 138831-86-4 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: None |
| References |
Lipford et al (1993) Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif. J. Immunology 150(4) 1212 PMID: 7679422Wick and Pfeifer (1996), Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP€independent presentation. Eur. J. Immunol. 26 2790 PMID: 8921970Karandikar et al (2019) New epitopes in ovalbumin provide insights for cancer neoepitopes. JCI Insight. 5(8) e127882 PMID: 30869653 Related data All epitopes >All immunology research areas > |
| Supplier | Isca Biochemicals Limited |
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