| Product Name | OXA (17-33) |
|---|---|
| Description |
OXA (17-33) is a truncated orexin fragment, identified as the shortest active peptide with 23-fold selectivity for orexin 1 (OX1) (EC50=8.29 nM) over orexin 2 (OX2) receptors (EC50 = 187 nM). |
| Synonyms | 343268-91-7, OX-010, OX010, OXA (17-33), YELLHGAGNHAAGILTL, YELLHGAGNHAAGILTL-NH2 |
| Molecular Weight | 1749 Da |
| Target | Orexin receptors |
| Amino Acid Sequence | YELLHGAGNHAAGILTL-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 343268-91-7 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: C terminal amide |
| References |
Darker et al (2001) Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor. Bioorg. Med. Chem. Lett. 11(5) 737 PMID: 11266181German et al (2013)Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett. 4(12) 1224 PMID: 24707347 Related areasAll peptides >All orexin receptor modulators >All neuroscience categories >All appetite regulation categories > |
| Supplier | Isca Biochemicals Limited |
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