P-selectin Monoclonal Antibody

Category: Antibodies
Catalog
E-AB-27318
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Product Name P-selectin Monoclonal Antibody
Description P-selectin,also known as GMP140 or CD62P,is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation,thrombosis,and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists,P-selectin is transported rapidly to the cell surface.
Synonyms CD62,CD62P,FLJ45155,GMP 140,GMP140,GMRP,Granule membrane protein 140,GRMP,LECAM3,P selectin,PADGEM,PSEL,P-selectin,SELP
Host Mouse
Clone 756
Immunogen Fusion protein of P-selectin
Isotype IgG2b
Reactivity Human
Applications ELISA, IHC, WB
Form PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Uniprot P16109
Background P-selectin,also known as GMP140 or CD62P,is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation,thrombosis,and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists,P-selectin is transported rapidly to the cell surface.
Supplier Elabscience

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