| Product Name | Parafibromin Polyclonal Antibody |
|---|---|
| Description | This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. CDC73 (Cell Division Cycle 73) is a Protein Coding gene. Diseases associated with CDC73 include Hyperparathyroidism-Jaw Tumor Syndrome and Parathyroid Carcinoma. Among its related pathways are Signaling by Wnt and Signaling by Hedgehog. GO annotations related to this gene include RNA polymerase II core binding. |
| Synonyms | Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein) |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from human Parafibromin |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q6P1J9 |
| Background | This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. CDC73 (Cell Division Cycle 73) is a Protein Coding gene. Diseases associated with CDC73 include Hyperparathyroidism-Jaw Tumor Syndrome and Parathyroid Carcinoma. Among its related pathways are Signaling by Wnt and Signaling by Hedgehog. GO annotations related to this gene include RNA polymerase II core binding. |
| Supplier | Elabscience |
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