| Product Name | Parasin I |
|---|---|
| Description | Parasin I is an amphipathic antimicrobial peptide derived from the N-terminus of histone H2A of the catfish Parasilurus asotus. Parasin I has a wide antimicrobial activity and is about 12-100 times more potent than magainin 2 against a wide spectrum of microorganisms, without any hemolytic activity. In response to epidermal injury the catfish secretes parasin I into the epithelial mucosal layer, suggesting that it produces parasin I from its histone H2A by a specific protease upon injury to protect against invasion by microorganisms. |
| Synonyms | 219552-69-9, H-KGRGKQGGKVRAKAKTRSS-OH, KGRGKQGGKVRAKAKTRSS, Parasin I , amphipathic, antimicrobial peptide |
| Molecular Weight | 2000.4 Da |
| Target | Antibacterials |
| Amino Acid Sequence | KGRGKQGGKVRAKAKTRSS |
| Form | Freeze dried solid |
| Purity | >95% BY HPLC |
| Cas Number | 219552-69-9 |
| Storage | Store dry, dark and frozen |
| Notes | Modifications: None |
| References |
Park et al (1998) Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett. 1998 437(3) 258 PMID: 9824303Koo et al (2008) Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides 29(7) 1102 PMID: 18406495Zhao (2015) Characterization of bioactive recombinant antimicrobial peptide parasin I fused with human lysozyme expressed in the yeast Pichia pastoris system. Enzyme Microb. Technol. 77 61 PMID: 26138401PubChem - Parasin I Related areas All antimicrobial peptides >All immunology research categories > |
| Supplier | Isca Biochemicals Limited |
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