| Product Name | Penetratin |
|---|---|
| Description |
Penetratin is a 16-mer peptide derived from the third helix of the Drosophila Antennapedia DNA binding domain that is mapped to be responsible for cellular internalization. Penetratin is able to translocate through the plasma membrane to the cytosol and nucleus, and can facilitate internalization of macromolecular cargoes into living cells, usually by the formation of a conjugate or fusion protein. Penetratin is commonly used as an alternative or complement to Tat peptide for enhancing the cellular uptake of nanoparticles. |
| Synonyms | Antennapedia peptide, Antennapedia (43-58) |
| Molecular Weight | 2246.8 Da |
| Amino Acid Sequence | RQIKIWFQNRRMKWKK |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 188842-14-0 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: None |
| References |
Pietersz and Apostolopoulos (2001) A 16-mer peptide (RQIKIWFQNRRMKWKK) from antennapedia preferentially targets the Class I pathway. Vaccine 19(11-12) 1397 PMID: 11163662Dupont et al (2011) Penetratin story: an overview. Methods Mol Biol. 683 21 PMID: 21053119Patel et al (2019) Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines. Sci Rep 9 6298 PMID: 31000738 Related areasAll cell penetrating peptides > |
| Supplier | Isca Biochemicals Limited |
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