| Product Name | Peroxiredoxin 2, 1-198aa, Human, Recombinant |
|---|---|
| Description | Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant human Peroxiredoxin 2 protein was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | NKEFB, PRP, PRX2, PRXII, TDPX1, TSA, PRDX2, Peroxiredoxin 2, MGC4104, Natural killer cell enhancing factor B, Natural Killer Enhancing Factor B, NKEF B, PRDX 2, TDPX1, Thiol Specific Antioxidant 1, Thiol specific antioxidant protein, Thioredoxin Dependent Peroxide Reductase 1, Thioredoxin Peroxidase 1, Torin. |
| Host | E. coli |
| Molecular Weight | 36.1 kDa (320 aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris pH 8.0, 2mM EDTA |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Kim K., et al. (2009), Oncol Rep, 21(6):1391-6. Kim JH., et al. (2008). Clin Cancer Res. 14(8):2326-33. |
| Background | Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant human Peroxiredoxin 2 protein was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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