| Product Name | Peroxiredoxin 6, 1-224aa, Human, Recombinant |
|---|---|
| Description | Peroxiredoxin 6, also known as PRDX6, is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell and can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Recombinant human peroxiredoxin 6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | 1-Cys, aiPLA2, AOP2, NSGPx, p29, PRX, Peroxiredoxin6, PRDX6, PRDX 6, PRDX-6, AA690119, Prdx6 rs3, 1 Cys, 1 Cys peroxiredoxin, 1 Cys PRX, 1 cysPrx, 24 kDa protein, 9430088D19Rik, Acidic calcium independent phospholipase A2, Antioxidant protein 2, Aop2 rs3, Brp 12, mKIAA0106, Ciliary body glutathione peroxidase, CP 3, EC 1.11.1.15, EC 1.11.1.7, EC 3.1.1, GPx, KIAA0106, Liver 2D page spot 40, Ltw4, Lvtw 4, MGC46173, Non selenium glutathione peroxidase, NSGPx, ORF06, OTTHUMP00000032693, Peroxiredoxin6, PHGPx, Phospholipase A2 lysosomal, PLA2, Prdx5, PRX, Red blood cells page spot 12, Thiol specific antioxidant protein, |
| Host | E. coli |
| Molecular Weight | 15.5 kDa (137 aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MPGGLLLGDV APNFEANTTV GRIRFHDFLG DSWGILFSHP RDFTPVCTTE LGRAAKLAPE FAKRNVKLIA LSIDSVEDHL AWSKDINAYN CEEPTEKLPF PIIDDRNREL AILLGMLDPA EKDEKGMPVT ARVVFVFGPD KKLKLSILYP ATTGRNFDEI LRVVISLQLT AEKRVATPVD WKDGDSVMVL PTIPEEEAKK LFPKGVFTKE LPSGKKYLRY TPQP |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Davison EJ., et al. (2009). Proteomics. 9(18):4284-97. Wu J., et al. (2009). Chem Res Toxicol. 22(4):668-75. |
| Background | Peroxiredoxin 6, also known as PRDX6, is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell and can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Recombinant human peroxiredoxin 6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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