| Product Name | PEX19, 1-296aa, Human |
|---|---|
| Description | PEX19, also known as Peroxin 19, localizes to the outer surface of peroxisomes in liver cells. It is essential for peroxisome biogenesis in Saccharomyces cerevisiae. It is apparently involved in the initial stage of peroxisome membrane assembly, before the import of matrix protein. Recombinant human PEX19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | Peroxisomal biogenesis factor 19, D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1 |
| Host | E. coli |
| Molecular Weight | 37.3 kDa (338aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MAAAEEGCSV GAEADRELEE LLESALDDFD KAKPSPAPPS TTTAPDASGP QKRSPGDTAK DALFASQEKF FQELFDSELA SQATAEFEKA MKELAEEEPH LVEQFQKLSE AAGRVGSDMT SQQEFTSCLK ETLSGLAKNA TDLQNSSMSE EELTKAMEGL GMDEGDGEGN ILPIMQSIMQ NLLSKDVLYP SLKEITEKYP EWLQSHRESL PPEQFEKYQE QHSVMCKICE QFEAETPTDS ETTQKARFEM VLDLMQQLQD LGHPPKELAG EMPPGLNFDL DALNLSGPPG ASGEQC |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | James G.L. et al. (1994) J Biol Chem. 269: 14182-14190 Gotte K. et al. (1998) Mol. Cell Biol. 18: 616-628. |
| Background | PEX19, also known as Peroxin 19, localizes to the outer surface of peroxisomes in liver cells. It is essential for peroxisome biogenesis in Saccharomyces cerevisiae. It is apparently involved in the initial stage of peroxisome membrane assembly, before the import of matrix protein. Recombinant human PEX19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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