| Product Name | PEX5 Monoclonal Antibody |
|---|---|
| Description | The peroxisomal targeting signal type1 (PTS1) receptor,PEX5,is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins,respectively,and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic,partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10,PEX12,PEX13,and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS),which is a lethal peroxisome biogenesis disorder. |
| Synonyms | FLJ50634,FLJ50721,FLJ51948,Peroxin 5,Peroxisome receptor 1,PEX5,PTS1 BP,PTS1 receptor,PTS1R,PXR1 |
| Host | Mouse |
| Clone | 345 |
| Immunogen | Fusion protein of PEX5 |
| Isotype | IgG1 |
| Reactivity | Human, Rat |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P50542 |
| Background | The peroxisomal targeting signal type1 (PTS1) receptor,PEX5,is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins,respectively,and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic,partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10,PEX12,PEX13,and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS),which is a lethal peroxisome biogenesis disorder. |
| Supplier | Elabscience |
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