PF4V1, 31-104aa, Human

Proteins, Recombinant
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Product Name PF4V1, 31-104aa, Human
Applications SDS-PAGE
Background PF4V1 belongs to the intercrine alpha (chemokine CxC) family. It is a inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis(in vitro). Binding to heparin is much weaker than in the close homolog PF4/CXCL4. Recombinant human PF4V1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 37.8 kDa (334aa)
NCBI Accession # NP_002611
Purity > 85% by SDS-PAGE
References Green CJ, Charles RS, et al. (1989). Mol Cell Biol. 9(4):1445-51.
Eisman R, Surrey S, et al. (1990). Blood. 76(2):336-44.
Struyf S, Burdick MD, et al. (2004). Circ Res. 95(9):855-7.
Kuo JH, Chen YP, et al. (2013). J Biol Chem. 288(19):13522-33.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms Platelet factor 4 variant, CXCL4L1, CXCL4V1, PF4-ALT, PF4A, SCYB4V1
Tag His-tag

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