| Product Name | Phospho glycogen synthase peptide 2 |
|---|---|
| Description |
Phospho glycogen synthase peptide 2 is a synthetic peptide substrate for glycogen synthase kinase 3 (GSK 3). Phospho glycogen synthase peptide 2 when immobolised can be used for affinity purification of protein-serine kinases. Phospho glycogen synthase peptide 2 can also be used to inhibit the human dual specificity protein kinase CLK2. |
| Synonyms | GS peptide 2 |
| Molecular Weight | 3029 Da |
| Target | Kinases |
| Amino Acid Sequence | YRRAAVPPSPSLSRHSSPHQS(P)EDEEE |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 851366-97-7 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: Ser-21 is phosphorylated |
| References |
Woodgett (1989) Use of peptide substrates for affinity purification of protein-serine kinases. Anal.Biochem. 180 237 PMID: 2554753Sutherland et al (1993) Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in Ins and growth factor signalling. Biochem.J. 296 15 PMID: 8250835Tanji et al (2002) A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta. J Biol Chem. 277(40):36955 PMID: 12147701 Related areasInhibition of human CLK2 using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrateAll kinase modulators >All substrate peptides > |
| Supplier | Isca Biochemicals Limited |
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