| Product Name | Phospho-IGF1R (Tyr1346) Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to IGF1R (Phospho-Tyr1346) |
| Synonyms | CD221 antibody; CD221 antigen antibody; IGF 1 receptor antibody; IGF 1R antibody; IGF I receptor antibody; IGF-I receptor antibody; Igf1r antibody; IGF1R_HUMAN antibody; IGFIR antibody; IGFIRC antibody; IGFR antibody; Insulin like growth factor 1 receptor antibody; Insulin like growth factor 1 receptor precursor antibody; Insulin-like growth factor 1 receptor beta chain antibody; Insulin-like growth factor I receptor antibody; JTK13 antibody; MGC142170 antibody; MGC142172 antibody; MGC18216 antibody; Soluble IGF1R variant 1 antibody; Soluble IGF1R variant 2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 1346(Q-P-Y(p)-A-H) derived from Human IGF1R . |
| Isotype | IgG |
| Target | IGF1R |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P08069 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. |
| Supplier | Cusabio |
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