| Product Name | PMAIP1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to PMAIP1 |
| Synonyms | Adult T cell leukemia derived PMA responsive antibody; APR antibody; APR_HUMAN antibody; ATL-derived antibody; Immediate early response protein APR antibody; Immediate-early-response protein APR antibody; NOXA antibody; Phorbol 12 myristate 13 acetate induced protein 1 antibody; Phorbol-12-myristate-13-acetate-induced protein 1 antibody; PMA induced protein 1 antibody; PMA-induced protein 1 antibody; PMA-responsive gene antibody; Pmaip1 antibody; Protein Noxa antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Full length fusion protein |
| Isotype | IgG |
| Target | PMAIP1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Uniprot | Q13794 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
| Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
