| Product Name | Polyclonal anti-Claudin 1 |
|---|---|
| Description | Polyclonal anti-Claudin 1 |
| Host | Rabbit |
| Clonality | Monoclonal |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Claudins are a family of over twenty proteins which are components of tight junctions. Tight junctions are specialized regions of cell-to-cell contact made up of a network of strands to act as a molecular 'gasket' for preventing the leakage of ions, water, etc., between cells.1 Claudin 1 has been shown to distinguish epithelial neoplasms from lymphomas, making it a useful marker for nearly all carcinomas.2 |
| References | Folpe AL, et al. Am J Surg Pathol. 2002; 26:1620-6. Soini Y. Histopathology. 2005; 47:551-60 |
| Supplier | MONOSAN |
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