| Product Name | Polyclonal antibody against A-1-Antitrypsin |
|---|---|
| Description | Polyclonal antibody against A-1-Antitrypsin |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | The immunohistochemical staining of Alpha-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for A-1-Antitrypsin may also be used in detection of benign and malignant lesions of an histiocytic nature. Sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with portal fibrosis of uncertain etiology. |
| References | Callea F, et al. J Hepatol. 1986; 2:389-401. Palmer PE, et al.Am J Clin Pathol. 1974; 62:350-4. Palmer PE, et al. Cancer. 1980; 45:1424-31. Raintoft I, et al. Hum Pathol. 1979; 10:419-24. Ramsay AD, et al. Appl Immunohistochem Mol Morphol. 2008; 16:140-7 |
| Supplier | MONOSAN |
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