Polyclonal antibody against Factor VIII-Related Antigen

Category: Antibodies
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MON-RTU1101
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Product Name Polyclonal antibody against Factor VIII-Related Antigen
Description Polyclonal antibody against Factor VIII-Related Antigen
Host Rabbit
Clonality Monoclonal
Immunogen Unknown or proprietery to MONOSAN and/or its suppliers
Reactivity Human
Applications IHC-P
Diluent Buffer Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Concentration n/a
Storage 2-8°C
Notes Anti-Factor VIII-Related Antigen antibody reacts with endothelial cells and neoplastic blood cells. This antibody has helped to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. Not all endothelial cells synthesize (or store) this molecule; therefore, it should not be surprising that not all tumors of endothelial differentiation (benign or malignant) react with this antigen.
References Nichols GE, et al. Am J Clin Pathol. 1992; 97:770-5. Falk S, et al. Am J Surg Pathol. 1993; 17:959-70. Meis-Kindblom JM, et al. Am J Surg Pathol. 1998; 22:683-97. Allison KH, et al. Am J Surg Pathol. 2004; 28:298-307. Peyvandi F, et al. Blood Transfus. 2011; 9 Suppl 2:s3-8
Supplier MONOSAN

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