| Product Name | Protein S100-A10, 1-97aa, Mouse |
|---|---|
| Description | S100A10 also known as S100 calcium binding protein A10 is a group of small Ca2+ binding proteins with molecular weight of 10-12 kDa. Intracellular S100 proteins usually function as modulators of their target proteins, and exert various roles such as regulation of protein phosphorylation, enzyme activity, Ca2+ homeostasis, cytoskeleton components, and transcription factors. Recent research suggests a role for S100A10 as a prognostic marker and potential therapeutic target in colorectal cancer. Recombinant mouse S100A10, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | 42C, AA409961, AL024248, CAL12; Cal1l, CLP11, p10, p11, S100a10 |
| Host | E. coli |
| Molecular Weight |
15.4kDa (131aa) confirmed by MALDI-TOF 13.5-18KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMPSQMEH AMETMMLTFH RFAGDKDHLT KEDLRVLMER EFPGFLENQK DPLAVDKIMK DLDQCRDGKV GFQSFLSLVA GLTIACNDYF VVNMKQKGKK |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Donato R., et al. (2001) Int J Biochem Cell Biol. 33(7):637-68. Shang J., et al. (2013) Tumor Biol. 34(6):3785-90. |
| Background | S100A10 also known as S100 calcium binding protein A10 is a group of small Ca2+ binding proteins with molecular weight of 10-12 kDa. Intracellular S100 proteins usually function as modulators of their target proteins, and exert various roles such as regulation of protein phosphorylation, enzyme activity, Ca2+ homeostasis, cytoskeleton components, and transcription factors. Recent research suggests a role for S100A10 as a prognostic marker and potential therapeutic target in colorectal cancer. Recombinant mouse S100A10, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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