Product Name | PTP4A2 Antibody |
---|---|
Description | Rabbit polyclonal antibody to PTP4A2 |
Synonyms | PTP4A2 antibody; PRL2 antibody; PTPCAAX2 antibody; BM-008 antibody; Protein tyrosine phosphatase type IVA 2 antibody; EC 3.1.3.48 antibody; HU-PP-1 antibody; OV-1 antibody; PTP(CAAXII) antibody; Protein-tyrosine phosphatase 4a2 antibody; Protein-tyrosine phosphatase of regenerating liver 2 antibody; PRL-2 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Fusion protein of human PTP4A2 |
Isotype | IgG |
Target | PTP4A2 |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, WB |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q12974 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |
Supplier | Cusabio |
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