Product Name | PTPN7, 1-360aa, Human |
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Description | PTPN7, also known as tyrosine-protein phosphatase non-receptor type 7 isoform 1, acts preferentially on tyrosine-phosphorylated MAPK1. This protein plays a role in the regulation of T and B-lymphocyte development and signal transduction. Recombinant human PTPN7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Synonyms | Tyrosine-protein phosphatase non-receptor type 7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI |
Host | E.coli |
Molecular Weight | 32.4 kDa (289aa), confirmed by MALDI-TOF |
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP |
Tag | His-tag |
Reactivity | Human |
Applications | SDS-PAGE |
Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT |
Concentration | 0.5 mg/ml (determined by Bradford assay) |
Purity | > 90% by SDS-PAGE |
Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
References |
Pettiford S.M., et al. (2000) Oncogene. 19:858-869 Nika K., et al. (2004) Biochem. J. 378:335-342 |
Supplier | ARP |
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