| Product Name | PTPRC Monoclonal Antibody,PE-Cy5 Conjugated |
|---|---|
| Description | Mouse monoclonal antibody against PTPRC onjugated to PE/Cy5 |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG2a |
| Target | PTPRC |
| Reactivity | Human |
| Applications | ELISA, FC, IF |
| Form | liquid |
| Diluent Buffer | Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Uniprot | P08575 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
4AA9 reacts with CD45, a 180-220 kDa leukocyte common antigen (LCA). CD45 antigen is expressed at high levels on all hematopoietic cells including T and B lymphocytes, monocytes, granulocytes, NK cells and dendritic cells, but is not expressed on non-hematopoietic cells. CD45 antibody has also been reported to react weakly with mature blood erythrocytes and platelets. CD45 is a protein tyrosine phosphatase receptor that is critically important for T and B cell antigen receptor-mediated activation *Target of immunosuppresive antibody treatment. 1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. 2. Trowbridge, IS and Thomas, ML. (1993) Annu. Rev. Immunol. 12:85. 3. Pulido, R et al., (1988) J. Immunol. 140:3851. 4. Roach, T et al., (1997) Curr. Biol. 7:408. |
| Supplier | Cusabio |
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