| Product Name | Raet1e, 29-227aa, Mouse, Baculovirus |
|---|---|
| Description | Raet1e, also known as retinoic acid early-inducible protein 1-epsilon, is a member of a family of cell-surface proteins that function as ligands for mouse NKG2D. All Rae-1 family members bind to mouse NKG2D, an activating receptor expressed on NK cells and some T cell subsets, resulting in the activation of cytolytic activity and cytokine production by these effector cells. Recombinant mouse Raet1e, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Retinoic acid early-inducible protein 1-epsilon, Raet1e |
| Host | Virus |
| Molecular Weight |
32.5kDa (288aa) 40-57KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | LDDAHSLRCN LTIKDPTSAD LPWCDVKCSV DEITILHLNN INKTMTSGDP GKMANATGKC LTQPLNDLCQ ELRDKVSNTK VDTHKTNGYP HLQVTMIYPQ SQGQTPSATW EFNISDSYFF TFYTENMSWR SANDESGVIM NKWKDDGDLV QQLKYFIPQC RQKIDEFLKQ SKEKPRSTSR SPSITQLTST SPLPPPSHSL EHHHHHH |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Diefenbach A., et al. (2000) Nat Immunol. 1:119-126. Cerwenka A., et al. (2001) Proc Natl Acad Sci USA. 98:11521-11526. |
| Background | Raet1e, also known as retinoic acid early-inducible protein 1-epsilon, is a member of a family of cell-surface proteins that function as ligands for mouse NKG2D. All Rae-1 family members bind to mouse NKG2D, an activating receptor expressed on NK cells and some T cell subsets, resulting in the activation of cytolytic activity and cytokine production by these effector cells. Recombinant mouse Raet1e, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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