| Product Name | RARRES2, 21-157aa, Human, Baculovirus |
|---|---|
| Description | RARRES2, as known as retinoic acid receptor responder protein 2, is a distant member of the Cystatin superfamily. Members of this superfamily contain at least two intra-chain disulfide bonds and an alpha-helical structure over a distance of about 100 amino acids. This protein was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. Also, it has been implicated in autocrine/paracrine signaling for adipocyte differentiation and also stimulation of lipolysis. Recombinant human RARRES2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Retinoic acid receptor responder protein 2, RARRES2, HP10433, TIG2, Chemerin |
| Host | Virus |
| Molecular Weight |
73.4kDa (635aa) 70-100KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | ADPELTEAQR RGLQVALEEF HKHPPVQWAF QETSVESAVD TPFPAGIFVR LEFKLQQTSC RKRDWKKPEC KVRPNGRKRK CLACIKLGSE DKVLGRLVHC PIETQVLREA EEHQETQCLR VQRAGEDPHS FYFPGQFAFS HHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Hatziagelaki E., et al, (2015) PLoS ONE 10:E0124935. Zabel BA., et al, (2014) Am J Clin Exp Immunol. 3:1-19. |
| Background | RARRES2, as known as retinoic acid receptor responder protein 2, is a distant member of the Cystatin superfamily. Members of this superfamily contain at least two intra-chain disulfide bonds and an alpha-helical structure over a distance of about 100 amino acids. This protein was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. Also, it has been implicated in autocrine/paracrine signaling for adipocyte differentiation and also stimulation of lipolysis. Recombinant human RARRES2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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