Rat anti-Endothelial Cell Protein Receptor, clone LMR-42 (Monoclonal)
| Product Name | Rat anti-Endothelial Cell Protein Receptor, clone LMR-42 (Monoclonal) |
|---|---|
| Description | Rat anti-Endothelial Cell Protein Receptor, clone LMR-42 (Monoclonal) |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | LMR-42 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | IHC-Fr, FC |
| Working Dilutions | IHC-fr (1:20), |
| Diluent Buffer | cell culture supernatant with 0.7% BSA and 0.1% sodium azide |
| Concentration | 100 ug/ ml |
| Storage | 2-8°C |
| Notes | The rat monoclonal antibody LMR-42 detects an outer-surface epitope of a 55 kDa plasma membrane protein overexpressed in several human non-Pgpmultidrug-resistant (MDR) tumor cell lines. Expression cloning revealed that the LMR-42 antigen is identical to the human endothelial cell protein Creceptor (EPCR). Protein C is the zymogen of the key anticoagulant enzyme, activated protein C (APC). |
| References | Flens MJ et al. Int J Cancer 1997; 73: 249. Scheffer GL et al. J Cancer 2002; 1535-42. Esmon CT et al. Crit Care Med 2004; 5 suppl: s298-301 |
| Supplier | MONOSAN |
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