| Product Name | Rat anti-MRP1, clone MRPr1 (Monoclonal) |
|---|---|
| Description | Rat anti-MRP1, clone MRPr1 (Monoclonal) |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | MRPr1 |
| Immunogen | 168 aa amino-proximal half of protein |
| Isotype | IgG2a |
| Reactivity | Human |
| Applications | IHC-Fr, FC, ICC, IHC-P, WB |
| Working Dilutions | ,,,,IHC-P (1:20-1:50) |
| Diluent Buffer | Serum free tissue culture supernatant with 0.7% BSA and 0.1% sodium azide |
| Concentration | 250 ug/ ml |
| Storage | 2-8°C |
| Notes | MRPr1 reacts with an epitope of MRP, a 180-195 kD transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPr1 was raised against a bacterial fusion protein of MRP, containing a segment of 168 amino acids in the amino-proximal half of the protein. MRPr1 does not cross-react with the human MDR1 and MDR3 gene products (Flens et al. 1994). |
| References | Cole S et al. Science 1992; 258: 1650-1654. Flens M et al. Cancer Res 1994; 54: 4557-4563. Zaman et al. Proc Nat Acad Sci 1994; 91: 8822-8826. Schadendorf et al. Am J Pathol 1995; 147: 1545-52. Nooter et al. Clin Cancer Res 1995; 1: 1301-10 |
| Supplier | MONOSAN |
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