| Product Name | Rat Disks large-associated protein 2 (DLGAP2) ELISA Kit |
|---|---|
| Description | Rat Disks large-associated protein 2 (DLGAP2) ELISA Kit has high sensitivity and excellent specificity for detection of Rat DLGAP2. No significant cross-reactivity or interference between Rat DLGAP2 and analogues was observed. The product of this gene is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. These kinases are a family of signaling molecules expressed at various submembrane domains and contain the PDZ, SH3 and the guanylate kinase domains. This protein may play a role in the molecular organization of synapses and in neuronal cell signaling. Alternatively spliced transcript variants encoding different isoforms have been identified, but their full-length nature is not known.Sequence analysis predicted that the 538-amino acid DLGAP2 shares 52% sequence similarity with DLGAP1 and contains four 14-amino acid repeats and 3 proline-rich regions. Binding analysis showed that DLGAP2, like DLGAP1, interacts with DLG4 and DLG1. This Rat Disks large-associated protein 2 (DLGAP2) ELISA Kit employs a two-site sandwich ELISA to quantitate DLGAP2 in samples. An antibody specific for DLGAP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyDLGAP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for DLGAP2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of DLGAP2 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | DLGAP2, DAP2, SAPAP2, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, discs large-associated protein 2 |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Rat |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 116681 |
| Storage | 2-8°C |
| Background | The product of this gene is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. These kinases are a family of signaling molecules expressed at various submembrane domains and contain the PDZ, SH3 and the guanylate kinase domains. This protein may play a role in the molecular organization of synapses and in neuronal cell signaling. Alternatively spliced transcript variants encoding different isoforms have been identified, but their full-length nature is not known.Sequence analysis predicted that the 538-amino acid DLGAP2 shares 52% sequence similarity with DLGAP1 and contains four 14-amino acid repeats and 3 proline-rich regions. Binding analysis showed that DLGAP2, like DLGAP1, interacts with DLG4 and DLG1. |
| Supplier | Abbkine |
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