| Product Name | RBBP9 Monoclonal Antibody |
|---|---|
| Description | RBBP9,also named as BOG,RBBP10,RBBP-9,RBBP-10 and Protein BOG,belongs to the RBBP9 family. It may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-_1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. RBBP9 is a tumor-associated serine hydrolase activity required for pancreatic neoplasia. It mediates suppression of TGF-_ signaling is required for E-cadherin expression as loss of the serine hydrolase activity leads to a reduction in E-cadherin levels and a concomitant decrease in the integrity of tumor cellÐcell junctions..RBBP9 protein levels were equivalent in paired primary tumor and nonneoplastic specimens |
| Host | Mouse |
| Clone | 456 |
| Immunogen | Fusion protein of RBBP9 |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | O75884 |
| Background | RBBP9,also named as BOG,RBBP10,RBBP-9,RBBP-10 and Protein BOG,belongs to the RBBP9 family. It may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-_1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. RBBP9 is a tumor-associated serine hydrolase activity required for pancreatic neoplasia. It mediates suppression of TGF-_ signaling is required for E-cadherin expression as loss of the serine hydrolase activity leads to a reduction in E-cadherin levels and a concomitant decrease in the integrity of tumor cellÐcell junctions..RBBP9 protein levels were equivalent in paired primary tumor and nonneoplastic specimens |
| Supplier | Elabscience |
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