RBPJ Monoclonal Antibody

Category: Antibodies
Catalog
E-AB-27538
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Product Name RBPJ Monoclonal Antibody
Description The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
Synonyms RBPJ,KBF2,IGKJRB1,IGKJRB,csl
Host Mouse
Clone 224
Immunogen Fusion protein of RBPJ
Isotype IgG1
Reactivity Human
Applications ELISA, WB
Form PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Uniprot Q06330
Background The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
Supplier Elabscience

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