| Product Name | Recombinant Bovine Complement C3 (C3), partial |
|---|---|
| Description | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). |
| Synonyms |
Cleaved into the following 12 chains: Complement C3 beta chain Complement C3 alpha chain C3a anaphylatoxin C3-beta-c Short name: C3bc Acylation stimulating protein Short name: ASP Alternative name(s): C3adesArg Complement C3b alpha' chain Complement C3c alpha' chain fragment 1 Complement C3dg fragment Complement C3g fragment Complement C3d fragment Complement C3f fragment Complement C3c alpha' chain fragment 2 |
| Host | E.coli |
| Molecular Weight | 39.5 |
| Amino Acid Sequence | SDLDDDIIPEEDIISRSQFPESWLWTVIEDLKQADKNGISTKLMNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAILYNYREAENLKVRVELLYNPAFCSLATAKKRHQQTITIPARSSVAVPYVIVPLKIGLHEVEVKAAVYNHFISDGVKKTLKVVPEGVRVNKTVAVRTLNPEHLGQ |
| Protein Length | Partial, 747-953aa |
| Tag | N-terminal 6xHis-SUMO-tagged |
| Reactivity | Bovine |
| Applications | SDS-PAGE |
| Form | Liquid, in Tris-based buffer, 50% glycerol |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| References | "The structure of bovine complement component 3 reveals the basis for thioester function."Fredslund F., Jenner L., Husted L.B., Nyborg J., Andersen G.R., Sottrup-Jensen L.J. Mol. Biol. 361:115-127(2006) |
| Background | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). |
| Supplier | Cusabio |
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