Recombinant Candida albicans Agglutinin-like protein 3 (ALS3), partial
| Product Name | Recombinant Candida albicans Agglutinin-like protein 3 (ALS3), partial |
|---|---|
| Description | Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells |
| Synonyms |
3D9 antigen Adhesin 3 |
| Host | E.coli |
| Molecular Weight | 37.9 |
| Amino Acid Sequence | VSVETESSTVTTAQTNPSVPTTESEVVFTTKGNNENGPYESPSTNVKSSMDENSEFTTSTAASTSTDIENETIATTGSVEASSPIISSSADETTTVTTTAESTSVIEQPTNNNGGGKAPSATSSPSTTTTANNDSVITGTTSTNQSQSQSQYNSDTQQTTLSQQMTSSLVSLHMLTTFDGSGSVIQHSTWLCGLITLLSLFI |
| Protein Length | Partial, 918-1119aa |
| Tag | N-terminal 10xHis-B2M-tagged and C-terminal Myc-tagged |
| Reactivity | Yeast |
| Applications | SDS-PAGE |
| Form | Liquid, in Tris-based buffer, 50% glycerol |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| References |
"The peptide-binding cavity is essential for Als3-mediated adhesion of Candida albicans to human cells." Lin J., Oh S.H., Jones R., Garnett J.A., Salgado P.S., Rusnakova S., Matthews S.J., Hoyer L.L., Cota E. J. Biol. Chem. 289:18401-18412(2014) |
| Background | Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells |
| Supplier | Cusabio |
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