Recombinant Dog Tight junction protein ZO-1 (TJP1), partial
| Product Name | Recombinant Dog Tight junction protein ZO-1 (TJP1), partial |
|---|---|
| Description | The N-terminal may be involved in transducing a signal required for tight junction assbly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells . |
| Synonyms | Tight junction protein 1Zona occludens protein 1Zonula occludens protein 1 |
| Host | E.coli |
| Molecular Weight | 18.7 |
| Amino Acid Sequence | VVATARGVFNNNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCASMTPDGWSFALKSSDSSSGDPKTWQNKCLPGDPNYLVGANCVSVLIDHF |
| Protein Length | Partial, 1633-1769aa |
| Tag | N-terminal 6xHis-tagged |
| Reactivity | Canine |
| Applications | SDS-PAGE |
| Form | Liquid, in Tris-based buffer, 50% glycerol |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| References | The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.Tsapara A., Matter K., Balda M.S.Mol. Biol. Cell 17:1322-1330(2006) |
| Background | The N-terminal may be involved in transducing a signal required for tight junction assbly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells . |
| Supplier | Cusabio |
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