Recombinant Human General transcription factor IIF subunit 2 (GTF2F2)

Category: Proteins
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CSB-EP010005HU
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Product Name Recombinant Human General transcription factor IIF subunit 2 (GTF2F2)
Description TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
Synonyms ATP-dependent helicase GTF2F2General transcription factor IIF 30 kDa subunitTranscription initiation factor IIF subunit beta , TFIIF-betaTranscription initiation factor RAP30
Host E.coli
Molecular Weight 44.2
Amino Acid Sequence AERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNEDLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAASENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD
Protein Length Full Length, 2-249aa
Tag N-terminal 6xHis-SUMO-tagged
Reactivity Human
Applications SDS-PAGE
Form Liquid, in Tris-based buffer, 50% glycerol
Purity Greater than 90% as determined by SDS-PAGE.
References Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II.Sopta M., Burton Z.F., Greenblatt J.Nature 341:410-414(1989)
Background TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
Supplier Cusabio

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