| Product Name | Recombinant Larimichthys crocea Hepcidin (hamp) |
|---|---|
| Description | Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages Has very strong antibacterial activity against the marine Gram-negative bacteria V.alginolyticus (MIC=24 µM), V.fluvialis, V.harveyis (MIC=12 µM) and V.parahaemolyticus (MIC=6 µM). Has antibacterial activity against the Gram-negative bacteria A.hydrophila (MIC=6 µM), E.coli (MIC=24 µM), and E.coli BL21(DE3)plysS (MIC=6 µM), and the Gram-positive bacteria B.cereus (MIC=24 µM), B.subtilis (MIC=6 µM), C.glutamicum (MIC=3 µM), M.luteus (MIC=3 µM), M.lysodeikticus, S.aureus (MIC=6 µM) and S.epidermis (MIC=12 µM). Possesses antifungal activity against A.niger (MIC=24 µM), F.graminearum (MIC24 µM) and F.solani (MIC=24 µM), but lacks antifungal activity against the yeasts P.pastoris GS115 and C.albicans. |
| Host | E.coli |
| Molecular Weight | 2.5 kDa |
| Amino Acid Sequence | RCRFCCRCCPRMRGCGICCRF |
| Protein Length | Full Length of Mature Protein, 65-85aa |
| Tag | NO-Tagged |
| Reactivity | Fish |
| Applications | SDS-PAGE |
| Form | Liquid, in Tris-based buffer, 50% glycerol |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| References |
"Isolation and characterization of a hepcidin peptide from the head kidney of large yellow croaker, Pseudosciaena crocea." Zhang J., Yan Q., Ji R., Zou W., Guo G. Fish Shellfish Immunol. 26:864-870(2009) |
| Background |
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages Has very strong antibacterial activity against the marine Gram-negative bacteria V.alginolyticus (MIC=24 µM), V.fluvialis, V.harveyis (MIC=12 µM) and V.parahaemolyticus (MIC=6 µM). Has antibacterial activity against the Gram-negative bacteria A.hydrophila (MIC=6 µM), E.coli (MIC=24 µM), and E.coli BL21(DE3)plysS (MIC=6 µM), and the Gram-positive bacteria B.cereus (MIC=24 µM), B.subtilis (MIC=6 µM), C.glutamicum (MIC=3 µM), M.luteus (MIC=3 µM), M.lysodeikticus, S.aureus (MIC=6 µM) and S.epidermis (MIC=12 µM). Possesses antifungal activity against A.niger (MIC=24 µM), F.graminearum (MIC24 µM) and F.solani (MIC=24 µM), but lacks antifungal activity against the yeasts P.pastoris GS115 and C.albicans. |
| Supplier | Cusabio |
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