REG4, 23-158aa, Human (Denatured)

Category: Proteins
Catalog
01-P2990
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Product Name REG4, 23-158aa, Human (Denatured)
Description REG4 also known as Regenerating islet-derived protein 4. This protein is calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. It may be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. Recombinant human REG4, fused to T7-tag at N-terminus, was expressed in E.coli.
Synonyms Regenerating islet-derived protein 4 isoform 1, GISP, RELP, REG-IV
Host E. coli
Molecular Weight 34.3kDa (302aa)
Amino Acid Sequence MASMTGGQQM GRGSHMDIIM RPSCAPGWFY HKSNCYGYFR KLRNWSDAEL ECQSYGNGAH LASILSLKEA STIAEYISGY QRSQPIWIGL HDPQKRQQWQ WIDGAMYLYR SWSGKSMGGN KHCAEMSSNN NFLTWSSNEC NKRQHFLCKY RP
Tag His-tag
Reactivity Human
Applications SDS-PAGE
Form Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
Concentration 1mg/ml (determined by Bradford assay)
Purity > 85 % by SDS-PAGE
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles.
References Strausberg RL., et al. (2000) Proc. Natl. Acad. Sci. u.S.A. 99 (26): 16899-903
Background REG4 also known as Regenerating islet-derived protein 4. This protein is calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. It may be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. Recombinant human REG4, fused to T7-tag at N-terminus, was expressed in E.coli.
Supplier ARP

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