| Product Name | Retinol Binding Protein 4 (RBP4) |
|---|---|
| Description | Retinol Binding Protein 4 (RBP4) belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. RBP4 is thought to link obesity with insulin resistance and Type 2 Diabetes. Present in plasma of healthy individuals at a level of approximately 40 mg/L, RBP4 levels are higher in individuals with impaired glucose tolerance and Type 2 Diabetes. RBP4 levels are increased in pregnant women, especially those with gestational diabetes. Increased levels of RBP4 levels are also seen in individuals with cardiovascular disease, as RBP4 levels appear to correlate with levels of APO B-containing lipoproteins-- LDL, VLDL, and small dense LDL. |
| Synonyms | Casein kinase II subunit alpha, EC 2.7.11.1, CK II, CK2-alpha |
| Molecular Weight | 21,000 Daltons |
| Form | Purified, in 50 mM Tris-HCl, 500 mM NaCl, pH 7.4 |
| Purity | > 98% |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| Supplier | ARP |
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