RGS2, 1-211aa, Human

Catalog
01-1796-2
$0.00
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Proteins, Recombinant
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More Information
Product Name RGS2, 1-211aa, Human
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MQSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T
Applications SDS-PAGE
Background RGS2, also known as G0S8, is a RGS family member and regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Recombinant human RGS2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 28.0 kDa (256aa) confirmed by MALDI-TOF
NCBI Accession # NP_002914
Purity > 90% by SDS-PAGE
References Tang KM., et al. (2003) Nat Med. 9(12):1506-12.
Santos de Araujo RM., et al. (2007) Cell Biochem Funct. 25(6):753-8.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms Regulator of G-protein signaling 2 24kDa, G0S8
Tag His-tag

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